- Special Supervisor, MVST: Pharmacology
- Cambridge Neuroscience Coordinator
My research is focused on understanding the mechanisms underlying neurodegeneration and abnormal behaviour in Huntington’s disease (HD). I am also interested in the role that changes in synaptic modulators play in neurological illness. The main portion of my research involves the study of motor, cognitive and social behaviour in mice (the R6/2 transgenic mouse model of HD in addition to Complexin knockout mice) in the context of HD. I am also interested in how the length of the CAG repeat affects the progression of the behavioural phenotype in the R6/2 mouse model of HD. Finally, my current work focuses on the cognitive enhancing properties of antidepressants in the context of HD.